![]() Specific biochemical lesions associated with Sn deficiency have not been reported and the biological chemistry of the element remains to be determined. Several tin compounds including organic tin derivatives were reported to be effective, indicating that the organism is capable of utilizing tin covalently bound to carbon. found the growth rate to be enhanced by nearly 60% if 1-2 ppm Sn was added as stannic sulfate to a highly purified diet fed in a plastic isolator environment. Tin has now been shown to be an essential nutrient for the growth of rats. However, there is little evidence to indicate that tin can be toxic.īiological interest in tin initially focused on its toxic potential to man through the contact of foods with tin-coated cans and tinfoil. Tin is still used to line certain cans, and acidic foods like canned pineapple and canned tomatoes can leach out tin from the inside of a can. If it functions as a nutrient in humans, typical daily ingestion of 1.5 to 5 mg per day more than meets requirements. ![]() Rigorous exclusion of tin from diets of laboratory animals impaired reproduction and caused other abnormal growth. There is some evidence that it is a required nutrient in animals, although it has no known metabolic function at the present time. Men over age 30 lose their hearing more than twice as fast as woman of the same age. There is also evidence for tin having cancer prevention properties.Ī federal study released in November of 1991 showed that men in recent generations have poorer hearing at any given age than in men in earlier generations. Tin has been shown to exert a strong induction effect on the enzyme heme oxygenase, enhancing heme breakdown in the kidney. Rats fed tin at 17.0 ng/gm show poor growth, reduced feeding efficiency, hearing loss, and bilateral (male pattern) hair loss, while rats fed 1.99 ug/gm were physiologically and anatomically normal tin was demonstrated to be an essential element by Schwarz in 1970. As a member of the fourth main chemical group of elements, tin has many chemical and physical properties similar to those of carbon, silica, germanium and lead. Originally the presence of tin in tissue was attributed to environmental contamination however, careful and detailed studies by Schwarz demonstrated that tin produced an acceleration of growth in rats and further met the standards for an essential trace element. 15 ppm (highest levels are found in the lungs and intestines). Sn – Tin is found in igneous rocks at 2 ppm shale at 6 ppm sandstone and limestone at 0.5 ppm fresh water at 0.00004 ppm sea water at 0.003 ppm soils at 2 to 200 ppm (strongly absorbed by humus) marine plants at 1 ppm land plants at 0.3 ppm (highest in bryophytes and lichens) marine animals at 0.2 to 20 ppm land animals at 0.
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